Immortals Medicine Zepbound KwikPen tirzepatide 2.5 mg injection pen on a blue background, GLP-1 weight management prescription in the Bryan Johnson Blueprint longevity protocol

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Immortals homepage biohacking lifestyle image featuring Bryan Johnson and his Blueprint longevity protocol

– Bryan Johnson
  • Support weight loss

Zepbound® KwikPen®

(tirzepatide)

From $600/mo*

Activates both GLP-1 and GIP receptors, the two gut hormones that signal appetite and satiety, supporting long-term weight loss.
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Not sure? Take the quiz

*Billed quarterly with a three-month commitment paid up front.
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HSA/FSA
reimbursable

Founded by Bryan
Johnson
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No insurance
required

Fast, discreet
shipping
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Licensed US
pharmacies

Unlimited follow-up with licensed physicians
Shield with medical cross icon representing HSA and FSA eligibility at Blueprint Immortals

HSA/FSA
reimbursable
Dollar sign icon representing transparent pricing at Blueprint Immortals

No insurance
required
Laboratory flask with checkmark icon representing tested formulas at Blueprint Immortals

Licensed US
pharmacies

Founded by Bryan Johnson

Fast, discreet shipping

Unlimited follow-up with licensed physicians

$0

Membership fees

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Immortals homepage biohacking lifestyle image featuring Bryan Johnson and his Blueprint longevity protocol

– Bryan Johnson
WHY ZEPBOUND®

Zepbound® targets two hormones that regulate appetite.

With Zepbound® Without Zepbound®
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.

HOW ZEPBOUND® WORKS

Reduces appetite.

Supports healthy weight loss.

Zepbound® activates both GLP-1 and GIP receptors, the two gut hormones that signal fullness and regulate fat metabolism.

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Activates GLP-1 and GIP receptors

Zepbound® selectively binds to and activates both the GLP-1 and GIP receptors, the targets for native gut hormones that regulate appetite and caloric intake.
Standing weight scale icon representing weight management at Blueprint Immortals

Weight loss supported

In clinical trials, once-weekly dosing produced up to 20.9% mean weight loss at 72 weeks in adults with high BMI.
Crossed-out fork and knife icon representing no fasting or dietary restriction at Blueprint Immortals

Reduces appetite

This can reduce appetite, leading to decreased calorie consumption. Zepbound® can also delay gastric emptying, extending the feeling of fullness after each meal.

HOW IMMORTALS MEDICINE WORKS

From intake to your door in three to seven days

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The same prescription framework as Bryan Johnson’s medical team.

Medical intake

Step 1

Medical intake

Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

A few minutes
Doctor review

Step 2

Doctor review

A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

Within 72 hours
Fast shipping

Step 3

Fast shipping

Approved medications ship directly to your door in discreet packaging.

2-5 business days
Unlimited messaging

Step 4

Unlimited messaging

Your doctor is available via chat any time for additional support. Video consults available.

Up to 12 months
Get Started

The same prescription framework as Bryan Johnson’s medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

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Why Immortals Medicine

Precision medicine protocols to support longevity

  • Proactive care

    Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

  • Transparent pricing

    No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

  • Board-certified doctors

    Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

  • Curated by longevity experts

    Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

What is Zepbound® KwikPen®?

Zepbound® (tirzepatide) is a once-weekly GIP/GLP-1 receptor agonist injection that is FDA-approved for chronic weight management in adults with a high BMI and at least one weight-related condition such as hypertension, dyslipidemia, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease. It is sometimes prescribed off-label by doctors within a longevity framework.

How do you take Zepbound® KwikPen®?

Zepbound® is a once-weekly subcutaneous auto injection delivered into the abdomen, thigh, or upper arm at any time of day, with or without meals. Rotate injection sites each week and follow the dosing instructions from your doctor.

What are the side effects of Zepbound®?

The most frequently reported side effects are nausea, diarrhea, vomiting, constipation, and abdominal pain, particularly when increasing dosage. Indigestion, injection-site reactions, fatigue, burping, hair loss, and acid reflux have also been reported. These are typically mild to moderate and tend to resolve as your body adjusts. Tell your doctor if side effects persist or feel disruptive.

Who shouldn't take Zepbound®?

Zepbound® is contraindicated in people with a personal or family history of medullary thyroid carcinoma or MEN 2 due to the boxed warning for thyroid C-cell tumor risk. It is also not recommended during pregnancy, in people with a history of pancreatitis, severe gastrointestinal disease, or active diabetic retinopathy. Extra caution is warranted for people on insulin or sulfonylureas, with active gallbladder disease, or with a history of depression or suicidal ideation. Your doctor will review your full medication list and health history before prescribing.

Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program

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