Immortals Medicine Semaglutide injectable amber vial with blue Weight Management label on a blue background, GLP-1 weight loss prescription therapy

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Immortals homepage biohacking lifestyle image featuring Bryan Johnson and his Blueprint longevity protocol

– Bryan Johnson

  • Support weight loss
  • Explore peptides
  • Support longevity

Personalized Semaglutide

Compounded Semaglutide with Glycine and B12

From $196/mo*

Can help suppress appetite and slow digestion. Personalized ingredients like Glycine and B12 may support muscle maintenance and nutrient deficiencies during a caloric deficit.

Medication Type
Get Started
Not sure? Take the quiz

*Billed quarterly with a three-month commitment paid up front.

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HSA/FSA
reimbursable

Founded by Bryan
Johnson

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No insurance
required

Fast, discreet
shipping

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Licensed US
pharmacies

Unlimited follow-up with licensed physicians

Shield with medical cross icon representing HSA and FSA eligibility at Blueprint Immortals

HSA/FSA
reimbursable

Dollar sign icon representing transparent pricing at Blueprint Immortals

No insurance
required

Laboratory flask with checkmark icon representing tested formulas at Blueprint Immortals

Licensed US
pharmacies

Founded by Bryan Johnson

Fast, discreet shipping

Unlimited follow-up with licensed physicians

$0

Membership fees

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Immortals homepage biohacking lifestyle image featuring Bryan Johnson and his Blueprint longevity protocol

– Bryan Johnson

WHY GLP-1s

Natural hormone breaks down in minutes. GLP-1s last days.

GLP-1s Natural GLP-1
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of a medication class or active ingredient. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes. References to medication classes, mechanisms, or published studies are intended to illustrate general pharmacologic concepts and do not establish that any specific medication, formulation, or treatment program will produce identical results. Compounded medications are not evaluated by the FDA for safety, quality or efficacy.

HOW GLP-1 RA WORKS

Supports feeling fuller for longer.

Semaglutide is a GLP-1 receptor agonist (GLP-1 RA) that mimics the GLP-1 hormone produced in the gut. Receptors are located in the brain, gut, heart, and pancreas, where activation supports appetite regulation, blood sugar balance, and metabolic function.

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Activates GLP-1 receptors

GLP-1 is a hormone your gut produces naturally, lasting only 1-2 minutes in the body. GLP-1 receptor agonists are engineered to activate the same receptors for days instead of minutes, providing sustained appetite regulation and metabolic support.

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Supports metabolic health

GLP-1 receptor agonists have been shown in studies to lower blood pressure, improve blood sugar regulation, and reduce lipid levels and inflammatory markers. These effects appear independent of weight loss, driven by direct GLP-1 receptor activation in the heart, blood vessels, and kidneys.

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Signals satiety

GLP-1 receptors in the brain suppress hunger and amplify fullness signals. The GLP-1 hormone can also slow digestion, extending a feeling of fullness after meals.

HOW IMMORTALS MEDICINE WORKS

From intake to your door in three to seven days

Get Started

The same prescription framework as Bryan Johnson’s medical team.

Medical intake

Step 1

Medical intake

Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

A few minutes
Doctor review

Step 2

Doctor review

A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

Within 72 hours
Fast shipping

Step 3

Fast shipping

Approved medications ship directly to your door in discreet packaging.

2-5 business days
Unlimited messaging

Step 4

Unlimited messaging

Your doctor is available via chat any time for additional support. Video consults available.

Up to 12 months
Get Started

The same prescription framework as Bryan Johnson’s medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

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Why Immortals Medicine

Precision medicine protocols to support longevity

  • Proactive care

    Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

  • Transparent pricing

    No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

  • Board-certified doctors

    Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

  • Curated by longevity experts

    Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

What is Personalized Semaglutide?

Semaglutide is used for weight management in overweight or obese adults. Additional ingredients (glycine and vitamin B12) support the body during treatment, potentially helping you hold onto muscle and avoid vitamin deficiencies. 

How do you take Personalized Semaglutide?

Personalized semaglutide is available via Immortals Medicine in a weekly injectable form.

What are the side effects of Personalized Semaglutide?

Nausea, vomiting, diarrhea, and constipation are most frequently reported. They typically improve within a few weeks as your body adjusts.

Who shouldn’t take Personalized Semaglutide?

Not recommended for people with a personal or family history of medullary thyroid cancer or MEN2. Your doctor will evaluate whether Personalized Semaglutide is appropriate for you.

Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program