Men's sex complex (3-in-1)
ED medication to
support longevity
A 3-in-1 formulation of apomorphine, tadalafil, and vardenafil to support men's sexual performance, desire, and longevity.
Proactive careDoctor-led treatment plans designed around your goals. 100% online. No insurance required.
Transparent pricingNo membership fees or hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctorsAccess to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Designed by longevity expertsEvery protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.
Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. *Billed quarterly with a three-month commitment paid up front.
Heightens arousal.
Improves performance.
Three ingredients to help you have better sex.
Activates desire signals
Apomorphine stimulates dopamine receptors, driving sexual arousal.
Inhibits PDE5
Tadalafil and vardenafil block PDE5, helping blood vessels relax.
Preserves nitric oxide
Blood vessels stay relaxed and circulation stays open, supporting erectile response.

Better sex + longevity
"ED is common, but most don't talk about it. Studies suggest >40% of affected men haven't even told their doctor. Interventions have benefits beyond better sex. Recent clinical evidence indicates the use of tadalafil can correlate to longer survival in men, in addition to potential benefits for heart health, metabolism, and even brain function."
– Bryan Johnson
Get StartedBryan Johnson is not a licensed medical professional and this page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Source: x.com/bryan_johnson
Why tadalafil
Blood vessels tighten as you age. Tadalafil helps keep them open.
Tadalafil works on one enzyme in your vascular system. This single action supports vascular health, sexual function, and longevity.
67.6%
Reported better sex
In the 12-week US trial, men taking as-needed tadalafil successfully completed intercourse in 67.6% of attempts, compared to only 24.1% with placebo.
Seftel AD et al., The Journal of Urology (2004)
82.8%
Reported improved erections
82.8% of tadalafil-treated men reported improved erections on the Global Assessment Question, versus 19.6% on placebo.
Seftel AD et al., The Journal of Urology (2004)
44%
Lower risk of death
A study of over 29,000 men found tadalafil users had a 44% lower risk of dying from any cause compared to non-users.
Kloner et al., Clinical Cardiology (2024)
The referenced clinical data are provided solely for educational and informational purposes to describe the known pharmacologic properties of the individual active ingredients. This information should not be interpreted as a claim that the compounded formulation will produce identical clinical outcomes, nor does it constitute a guarantee of therapeutic equivalence to any FDA-approved product.

Supports longevity
Men's Sex Complex (3-in-1)
Three actives: apomorphine, tadalafil, vardenafil
An as-needed sublingual tablet taken 30 to 60 minutes before sex
Heightens arousal. Improves performance.
Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness.
Not sure where to start?
Answer a few questions about your health goals to get a treatment recommendation. A physician reviews every recommendation, and there is no charge until your prescription is approved.
Get a Recommendation
Why Immortals Medicine
Precision medicine protocols
to
support longevity
No insurance
requiredHSA/FSA reimbursable
Doctor review within 72 hours
US-licensed, board-certified
Fast, discreet shipping
2 to 5 business days
Unlimited physician follow-up
Up to 12 months
Common questions
Questions, answered
Men's Sex Complex is an as-needed sublingual tablet taken 30 to 60 minutes before sex. It contains apomorphine, tadalafil, and vardenafil, which can support erectile response and sexual performance.
Dissolve half to one full tablet under the tongue or in the cheek 30 to 60 minutes before sexual activity. Not intended for daily use. Use only as needed.
Side effects may include headache, flushing, nasal congestion, dizziness, lightheadedness, and nausea.
Men's Sex Complex is not intended for use in women. Men's Sex Complex cannot be taken with nitrates, or by people with unstable cardiovascular disease. Your doctor will evaluate if Men's Sex Complex is appropriate for you.
Daily tadalafil is a single active taken every day. Men's Sex Complex contains three actives and is taken only when needed, 30 to 60 minutes beforehand. Your provider will recommend one based on your intake.
Compounded medications are customized prescriptions prepared by licensed compounding pharmacies. These are tailored to a patient's specific clinical needs, such as personalizing a dose based on health goals for which commercially available doses may not be appropriate. While these medications use doctor-trusted ingredients from licensed pharmacies, the compounded formularies are not FDA-approved.
Immortals Medicine is available to adults 18+ in eligible U.S. states only. Certain medications are not available in certain states.
From $48/mo, billed quarterly with a three-month commitment paid up front. No membership fees or insurance requirements. You are only charged after a physician approves your treatment.
Tell your provider. Men's Sex Complex contains tadalafil, so taking both means taking the same drug class twice. Your doctor will review your full medication list before prescribing.
Tadalafil (generic for Cialis®) is an FDA-approved PDE5 inhibitor prescribed for erectile dysfunction and benign prostatic hyperplasia. Some physicians also prescribe it off-label at low daily doses within longevity protocols.
This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program. Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use.